EFECTOS DEL MALATHION SOBRE LA ESPERMATOGÉNESIS DE RATONES MACHOS JÓVENES DE LA CEPA BALB-C53.

Abstract

The Present work aims at establishing the toxic effects on spermatogenesis of a single injection of the pesticide Malathion in young mice. For it, 50 young male Balb-C53 mice of 30 days of age was distributed aleatorily in two groups: Experimental (E) that received 1/3 de la LD50 of the commercial Malathion (Extrathion) diluted in corn oil injected intraperitoneally, and another Control (C) that only received corn oil for the same road. Treated mice and their controls were sacrificed in groups of 5 at: 4, 8, 18, 28 and 40 days after injection of the Malathion, for then to measure the count and morphology spermatic. After the injection of the Malathion was observed decrease of the spermatic count at 28 and 40 days postinjection (E: 458,00 and 519,80millons esp./ml vs C: 683,60 y 796,40millons esp./ml respectively, p£0,05) and increase of the teratozoospermia at 4 and 8 days postinjection (E: 13,60 y 8,40 % de esp. abnormal vs C: 4,60 y 2,40 % de esp. abnormal respectively, p£0,05). In conclusion the administration of a single dose of Malathion intraperitoneally it can affect the spermatogenesis of the young male mice.